Detalhe da pesquisa
1.
A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response.
Cell
; 172(5): 1007-1021.e17, 2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29474905
2.
Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1.
Mol Cell
; 83(14): 2398-2416.e12, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402365
3.
Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination.
Mol Cell
; 83(13): 2347-2356.e8, 2023 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37311462
4.
An epigenetic barrier sets the timing of human neuronal maturation.
Nature
; 626(8000): 881-890, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38297124
5.
TET2 guards against unchecked BATF3-induced CAR T cell expansion.
Nature
; 615(7951): 315-322, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36755094
6.
Epigenetic dysregulation from chromosomal transit in micronuclei.
Nature
; 619(7968): 176-183, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37286593
7.
Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis.
Mol Cell
; 81(8): 1749-1765.e8, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33657400
8.
Anatomic position determines oncogenic specificity in melanoma.
Nature
; 604(7905): 354-361, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35355015
9.
An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions.
EMBO J
; 42(24): e114221, 2023 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37987160
10.
A gene-environment-induced epigenetic program initiates tumorigenesis.
Nature
; 590(7847): 642-648, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33536616
11.
CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis.
Blood
; 141(20): 2508-2519, 2023 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36800567
12.
α-Ketoglutarate links p53 to cell fate during tumour suppression.
Nature
; 573(7775): 595-599, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31534224
13.
A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.
Mol Cell
; 67(2): 308-321.e6, 2017 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28732206
14.
HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression.
Blood
; 139(18): 2797-2815, 2022 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35286385
15.
BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation.
Blood
; 139(25): 3630-3646, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35421216
16.
UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth.
Proc Natl Acad Sci U S A
; 118(31)2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34330832
17.
Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1-mutated acute myeloid leukemia.
Blood
; 137(10): 1377-1391, 2021 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32871587
18.
Synergistic targeting of FLT3 mutations in AML via combined menin-MLL and FLT3 inhibition.
Blood
; 136(21): 2442-2456, 2020 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32589720
19.
2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation.
Proc Natl Acad Sci U S A
; 116(26): 12851-12856, 2019 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31182575
20.
Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis.
Blood
; 132(12): 1265-1278, 2018 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30064973